Relevant for Research Area

C - Applications





Dr. Andreas Weltin

Dr. Jochen Kieninger


The project aims to identify and discriminate the mechanisms causing electrode degradationduring electrical neural stimulation, even when operated within "safe limits." By combining in situmonitoring of the electrode's potential on the electrochemical scale during current-controlledstimulation with a phenomenological description of the effects on a submicron level, theelectrochemical reactions during different stages of degradation will be assessed. The approachbenefits from the IMBIT's Soft-FIB and a newly developed high-speed electrometer amplifier,allowing electrochemical potential monitoring parallel to current-controlled stimulation.

Previous Related Publication

Merrill, D. R.; Bikson, M.; Jefferys, J. G. R. Electrical Stimulation of Excitable Tissue: Designof Efficacious and Safe Protocols. J Neurosci Meth 2005, 141 (2), 171-198.

Cogan, S. F.; Ludwig, K. A.; Welle, C. G.; Takmakov, P. Tissue Damage Thresholds duringTherapeutic Electrical Stimulation. J Neural Eng 2016, 13 (2), 021001.

Durisin, M.; Krause, C.; Arnoldner, C.; Kontorinis, G.; Buechner, A.; Lenarz, T.; Lesinki-Schiedat, A.; Profant, O.; Neuburger, J. Electron Microscopy Changes of Cochlear ImplantElectrodes with Permanently High Impedances. Cochlear Implant Int 2013, 12 (4), 228-233.

Doering, M.; Kieninger, J.; Urban, G. A.; Weltin, A. Electrochemical MicroelectrodeDegradation Monitoring: In Situ Investigation of Platinum Corrosion at Neutral pH. J Neural Eng2022, 19 (1), 016005.