TransVR

TRANSLATIONAL VR PARADIGMS FOR NEUROSCIENCE: FROM RODENTS TO HUMANS

Summary

The proposed TransVR projects aims to develop and test virtual reality (VR) paradigms for translational research on visuomotor and spatial navigation brain functions in rodents and humans. The study will investigate the use of VR as a tool for studying brain functions related to spatial navigation and motor skills in both rodents and humans, which could have significant implications for translational research in neuroscience.

The proposed research will involve developing and testing VR environments that mimic real-world scenarios and tasks, based on our (IMBIT-co-funded) EEG-VR paradigm [1] as well as our work in rodents. These VR environments will be used to study the brain regions and circuits involved in spatial navigation and motor skills in rodents and humans. The study will employ a variety of techniques, including behavioral assays, electrophysiological recordings, and imaging techniques, to measure and analyze the neural activity of subjects during VR tasks.

The specific work in TransVR aims to establish the reliability and validity of these VR paradigms as a tool for translational research on visuomotor and spatial navigation brain functions. This research could have significant implications for the development of new treatments and therapies for neurological disorders that affect spatial navigation and motor skills.

Overall, this research proposal seeks to contribute to the development of new tools and techniques for translational research in neuroscience, particularly in the areas of visuomotor and spatial navigation brain functions. By using VR as a tool for investigating these functions in both rodents and humans, the proposed study aims to provide new insights into the neural mechanisms underlying these processes and also to lay foundations to develop new treatments and therapies for neurological disorders.