Relevant for Research Area

C - Applications


Microelectrode recordings allow for the simultaneous quantification of the activity of small neuronal ensembles (multi-unit activity, MUA) and Local Field Potentials (LFPs). So far it is still unclear to what extent MUA (>500 Hz) contributes to the generation of the LFP (<500 Hz). It has been proposed that the relation between these different scales varies depending on the underlying neuronal morphology, the synaptic distribution and the correlation of synaptic activity.

Publications and Achievements

·         Heers, M., Chowdhury, R. A., Hedrich, T., Dubeau, F., Hall, J. A., Lina, J. M.,Grova, C. & Kobayashi, E. (2016). Localization accuracy of distributed inverse solutions for electric and magnetic source imaging of interictal epileptic discharges in patients with focal epilepsy. Brain topography, 29(1), 162-181.

·         Zijlmans, M., Worrell, G. A., Dümpelmann, M., Stieglitz, T., Barborica, A., Heers, M., Ikeda, A., Usai, N. & Le Van Quyen, M. (2017). How to record highfrequency oscillations in epilepsy: A practical guideline. Epilepsia, 58(8), 1305-1315. [among four most shared review articles, Epilepsia 2017 & among 20 most downloaded articles within 1 year after publication in Epilepsia]

·         Heers, M., Helias, M., Hedrich, T., Dümpelmann, M., Schulze-Bonhage, A., & Ball, T. (2018). Spectral bandwidth of interictal fast epileptic activity characterizes the seizure onset zone. NeuroImage: Clinical, 17, 865-872. [among 25 most downloaded articles, NeuroImage Clinical 1-5/2018]

·         Behncke, Joos, et al. "Probabilistic neuroanatomical assignment of intracranial electrodes using the ELAS toolbox" Submitted to Journal of Neuroscience Methods

·         Glasstetter, Martin, et al. "Spectral estimation of movement related EEG activity using sine and Slepian multitaper: A comparison" in preparation